Pyridine, 3-chloro-5-methyl- - Names and Identifiers
Pyridine, 3-chloro-5-methyl- - Physico-chemical Properties
Molecular Formula | C6H6ClN
|
Molar Mass | 127.57 |
Density | 1.150±0.06 g/cm3(Predicted) |
Boling Point | 176.7±20.0 °C(Predicted) |
Flash Point | 75.7°C |
Vapor Presure | 1.45mmHg at 25°C |
pKa | 3.24±0.20(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.526 |
Pyridine, 3-chloro-5-methyl- - Introduction
3-chloro-5-methylpyriridine is an organic compound with the chemical formula C6H6ClN. The following is a description of the properties, uses, preparation and safety information of 3-chloro-5-methylpyriridine:
Nature:
-Appearance: 3-chloro-5-methylpyriridine is a colorless to yellow liquid.
-Solubility: Can be dissolved in most organic solvents, insoluble in water.
-Odor: has a special aromatic smell.
Use:
- 3-CHLORO-5-METHYLPYRIDINE is commonly used as a pharmaceutical intermediate and has important applications in the synthesis of pharmaceuticals and pesticides.
-It can also be used as a catalyst and solvent, as well as a reagent in certain chemical reactions.
Method:
The preparation of 3-CHLORO-5-METHYLPYRIDINE can be completed by the following steps:
1. From 2-methylpyridine, chlorination reaction is carried out under alkaline conditions to chlorinate the methyl group in 2-methylpyridine to 3-chloro-2-methylpyridine.
2. A chlorination reaction was further carried out under acidic conditions to chlorinate the 2-position methyl group in 3-chloro-2-methylpyridine to 3-chloroo-5-methylpyrridine.
Safety Information:
- 3-CHLORO-5-METHYLPYRIDINE is irritating and corrosive and should be handled carefully to avoid contact with skin and eyes.
-Use with chemical protective gloves, goggles and protective clothing.
-In case of contact, rinse immediately with plenty of water and seek medical help.
-In storage and handling, to follow the chemical safety procedures, and store it in a cool, dry, well-ventilated place, away from fire and flammable materials.
Last Update:2024-04-09 15:17:54